![]() ![]() M., “Translation of near-infrared fluorescence imaging technologies: emerging clinical applications,” Annu. Network, “NCCN clinical practice guidelines in oncology: antiemesis,” V.1.2010. ![]() SLNB with axillary lymph node dissection for node-positive breast cancer patients: experience from the SEER database,” Ann. , “Trends in and outcomes from sentinel lymph node biopsy (SLNB) alone vs. J., “A comparison of observational studies and randomized, controlled trials,” N. , “American Society of Clinical Oncology guideline recommendations for sentinel lymph node biopsy in early-stage breast cancer,” J. Handheld near-infrared fluorescence imaging projective imaging sentinel lymph node surgical navigation. ![]() Our ex vivo and in vivo experiments imply the clinical utility of deploying the proposed device for image-guided surgical interventions in resource-limited settings. Clinical utility for image-guided surgery is demonstrated in a clinical trial where sentinel lymph nodes in breast cancer patients are identified and resected under the guidance of projective imaging. Technical feasibility for projective imaging is verified in an ex vivo model of chicken breast tissue using indocyanine green as a fluorescence agent. Traditionally, the main data source for shoreline acquisition has been. The proposed device is able to achieve a projection resolution higher than 314 μm and a planar projection bias less than 1 mm at a projection field of view of 58 × 108 mm2 and a working distance of 27 cm. For the Landsat 8 and Sentinel-2 shorelines, the mean error reaches 3.06 m (5.79. It is calibrated at the detected working distance for seamless coregistration between fluorescence emission and projective imaging at the target tissue site. The device integrates a laser diode light source module, a camera module, a projector, an ultrasonic distance sensor, a Raspberry Pi single-board computer, and a battery module in a rugged handheld unit. We propose a handheld projective imaging device for orthotopic projection of near-infrared fluorescence images onto target biological tissue at visible wavelengths without any additional visual aid. ![]()
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